Applications of Clinical Spectrometry
Mass spectrometry has become an indispensable tool for clinical research and diagnostics. By providing detailed molecular information, it allows clinicians and researchers to gain insights that would not be possible through traditional techniques. Some key applications of clinical mass spectrometry include:
Metabolomics Analysis
Metabolomics analyzes all small molecule metabolites present in a biological sample such as blood, urine or tissues. This provides a snapshot of an individual's metabolic state which can yield clinically relevant information. Changes in metabolite levels have been associated with various diseases. Clinical Mass Spectrometry is well-suited for metabolomics due to its high sensitivity and ability to simultaneously measure a wide range of metabolites. This technique is being used to study metabolic perturbations related to diabetes, cancer and other conditions.
Protein Biomarker Discovery
The identification of protein biomarkers can facilitate early disease detection and monitoring of treatment response. Mass spectrometry enables comprehensive analysis of the proteome through techniques like gel electrophoresis, antibody/antigen detection and mass profiling of peptides/proteins.
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